不同病程精神分裂症患者家庭干预效果比较

Chronicity of illness and effect of family intervention in schizophrenia

目的： 了解精神分裂症病程对家庭干预效果的影响。 方法： 对病程＜ ５ 年与≥５ 年二组共１７８ 例精神分裂症患者的家属进行为期一年的综合式家庭干预， 并对干预效果进行比较。 结果：家庭干预后患者病程＜ ５ 年组，焦虑抑郁的发生率减少７８５７％ ，抑郁的严重程度明显减轻（ Ｐ＜ ００１），以功能失调性状况评定量表 （ Ｄ Ａ Ｓ） 评定的社会功能缺损程度明显减轻 （ Ｐ＜ ００１）， 年复发率下降５１８６％ ， 比病程≥５ 年组的情况好得多。 结论： 家庭干预有助于病人康复， 早期干预效果更好。

Objective:To study the relationship between chronicity of illness and effect of family intervention in schizophrenia. Method:178 patients with diagnosis of schizophrenia were divided into two groups according to duration of illness(<5 and ≥5 years). A one year family intervention program was instituted with clinical symptoms and social functioning compared, the latter using DAS. Results:Comparing between the two groups,there was 78 57% decrease in the occurrence of anxiety depressive symptoms with significant amelioration of severity of depression ( P <0 01) in subjects with less than 5 years of illness. There was also significant decrease in the impairment of social functioning as measured by DAS ( P <0 01) and relapse rate in the same group. Conclusion:Early family intervention is useful in the treatment of schizophrenia.