胺碘酮联合镁剂治疗急性心肌梗死室性心律失常的疗效观察

Observation of the Efficacy of Aiodarone Combined with Magnesium in Treatment of Acute Myocardial Infarction Ventricular Arrhythmias

目的观察胺碘酮联合镁剂治疗急性心肌梗死(AMI)室性心律失常的临床疗效。方法来我科行急诊抢救的69例急性心肌梗死室性心律失常患者随机分为观察组35例和对照组34例,观察组给予胺碘酮联合门冬氨酸钾镁静脉滴注;对照组则给予利多卡因静脉注射。观察两组患者的临床疗效。结果观察组的总有效率为88.6%,对照组总有效率为61.8%,两组比较差异有统计学意义(P<0.05);观察组的室颤发生率和病死率分别为2.9%、0%,明显低于对照组,差异有统计学意义(P<0.05)。结论胺碘酮联合镁剂治疗急性心肌梗死室性心律失常疗效确切,能显著改善AMI预后。

Objective To observe the clinical effects of amiodarone combined with magnesium in treatment of acute myocardial infarction with ventricular arrhythmias. Methods 69 patients of acute myocardial infarction with ventricular arrhythmias were divided into the observation group （35 cases） and the control group （34 cases）, the observation group were treated by amiodarone combined with potassium magnesium aspartate, ivdrip, and the control group were treated by lidocaine, intravenous injection. The clinical efficacy of the two groups was observed. Results The total effective rate of the observation group was 88.6% ,and the control group 61.8%, the difference was statistically significant （P〈0.05）; the incidence of ventricular fibrillation and mortality in the observation group were 2.9%, 0%,it was significantly lower than the control group, the difference was statistically significant（P〈0.05）. Conclusion The effect of amiodarone combined with magnesium in treatment of acute myocardial infarction ventricular arrhythmias is effective, it can significantly improve the prognosis of AMI.