雾化吸入布地奈德混悬液治疗小儿哮喘的临床观察

The Clinical Observation of Aerosol Inhaled Budesonide on Suspension the Young Child With Acute Asthma Attack

目的评价布地奈德雾化悬液雾化混吸入治疗小儿急性哮喘发作的效果。方法选择在本院就诊的小儿哮喘急性发作患者100例,入院后随机分为观察组和对照组各50例,观察组给予布地奈德雾化混悬液,对照组辅以筒式吸舒吸入布地奈德气雾剂吸入治疗,评价两组治疗效果。结果观察组总有效率为96.00%,高于对照组的总有效率(82.00%),两组差异比较具有统计学意义(P<0.01)。结论布地奈德雾化悬液雾化吸入治疗急性哮喘使用较方便,患儿用药依从性高,副作用少,可以建议临床进一步推广。

Objective To evaluate budesonide inhalation suspension aerosol treatment of pediatric patients with acute asthma attack results. Methods 100 patients with acute asthma attack were randomized after admission：50 cases for the observation group,50 cases as control group. Observation group received budesonide aerosol suspension per lmL （containing budesonide 0.5mg） plus saline to 2mL,2 times a day through the air compression pump inhalation;control group,accompanied by drum-priming Shu inhaled budesonide aerosol per day 400-800ug,2 times, inhalation therapy. Results Observation group,the total effective rate was 96.00% higher than that of the total effective rate was 82.00%, statistically significant （P〈0.01）.Two groups of nebulized bronchodilators in some patients, when both the hand shake, muscle trembling, irritability and other symptoms, were characterized by withdrawal symptoms following; two groups were no other significant adverse reactions. Conclusion Budesonide inhalation suspension aerosol treatment of acute asthma attacks more effective than use of auxiliary tools inhaled budesonide aerosol, and easy to use,without any special tie, medication compliance is high ,there is no gas propellant fluorine Lyon, side effects, could suggest the clinical further applying.