维吾尔药罗勒乙酸乙酯提取物抗炎作用的研究

Study on the anti-inflammatory effect of an ethyl acetate extraction of Uygher Medicine Ocimum Basilicum L

目的探讨维吾尔药罗勒乙酸乙酯提取物抗炎作用。方法采用二甲苯所致小鼠耳肿胀模型,角叉菜胶所致小鼠足肿胀模型及小鼠棉球肉芽肿模型来观察罗勒乙酸乙酯提取物的抗炎作用。结果与阳性对照组相比,乙酸乙酯提取物对二甲苯所致小鼠耳肿胀度有显著的抑制作用(P<0.01)。与对照组相比,对角叉菜胶所致小鼠足肿胀及小鼠棉球肉芽肿的形成有显著的抑制作用(P<0.001)。结论维药罗勒乙酸乙酯提取物有明显的抗炎作用。

OBJECTIVE To study on the anti-inflammatory effect of an ethyl acetate extractions of Uygher Ocimum Basilicum L.（OBL）.METHODS The anti-inflammatory effects of OBL extraction was observed by adapts Xylene induced mouse ear edema model,mouse pow swollen induced by carrageenon and using the modal of mouse granulation.RESULTS Compared with the positive contrast,the OBL ethyl acetate extractions have a signifocantly good effect to decrease the Xylene induced mouse ear edema（P〈0.01）.Compared with the control group,mouse pow swollen induced by carrageenan and the model of mouse granulation were decreased significantly（P〈0.001）.CONCLUSION The OBL ethyl acetate extractions have anti-inflammatory effect.