氨溴索雾化吸入治疗慢性阻塞性肺疾病急性加重期疗效观察

Effect of ambroxol by atomizing inhalation in treating acute exacerbation of chronic obstructive pulmonary disease

目的探讨氨溴索雾化吸入治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)的临床疗效和安全性。方法 70例AECOPD患者随机分成治疗组和对照组,治疗组给予氨溴索氧驱动雾化吸入;对照组给予氨溴索静脉滴注。结果治疗组总有效率明显高于对照组,两组间有显著的差异(P<0.05)。均未见明显副作用。结论氨溴索雾化吸入治疗AECOPD疗效确切。

OBJECTIVE To evaluate the effect of ambroxol in the treatment of acute exacerbation of chronic obstructive pulmonary disease（AECOPD）by oxygen-driven atomizing inhalation.METHODS Seventy cases with AECOPD were separated into treatment group（35 cases）and control group（35 cases）randomly.The treatment group was administrated with oxygen-driven atomizing inhalation of ambroxol.The control group was administrated with intravenous injecting ambroxol.RESULTS The total effective rate in the treatment group and the control group was 90% and 80% respectively,the difference were statistically significant（P〈0.05）.No obviously side effects were observed.CONCLUSION Atomization inhaling ambroxol is an effective and safe way to treat AECOPD.