摘要
儿童急性淋巴细胞白血病（ＡＬＬ）处于完全缓解（ＣＲ）期的２２例患儿，在不同时期分别采用三种不同的大剂量氯甲喋呤（ＨＤＭＴＸ）治疗，观察毒副反应，对不同剂量的毒副反应进行了对比分析，结果显示不同剂量的氨甲喋呤（ＭＴＸ）毒副作用相似，认为采用３．０ｇ／（ｍ２·次）的剂量能够耐受，有利于提高疗效。
Three kinds of different high dosage of metrotrexate were used for treatment on childrenwith acute lymphoblastic leukemia had relieved completely. The toxicity and side effects ofmetrotrexate of different dosage were studied. The result shows that the patients can endurethe toxicity and side effects of metrotrexate with three kinds of different dosage, and the toxicity and side effect is no different. We think that total 3 gram. time dosage can increasetreatment effect.
出处
《中国小儿血液》
1999年第4期145-147,共3页
China Child Blood
