慢性扁桃体炎遗传规律及基因频率研究

INQUIRE INTO THE GENETIC LAW AND GENE FREQUENCY OF CHRONIC TONSILLITIS

通过对慢性扁桃体炎的抽样调查,发现该病与遗传有关。共调查人数2478人.患病74人,44个完整家系。群体患病率为2.98％,Ⅰ级亲患病率为24.7％,两者有高度显著性差异(p<0.01)。基因颇率为0.173。并通过家系分析和等位基因频率测验法,证明该病为常染色体隐性遗传,并可受环境等因素影响而表现度减弱或外显不全。

Tonsillitis was somewhat related to inheritance according to sampling survey.2478 persons and 44 family members were examined, whom 74 (3.0%) had tonsillitis, with the morbidity in directly-related members of the fami- lies being 24.7%.Genc frequency is 0.173. It is sugg suggested that autosomaI reccsscsive inheritance Played a role in it. but morbidity may be influenced by other factors such as cnvironment.