摘要
本文分析了瘢痕疙瘩四个家系,发现患者28人,其中男13人,女15人,一对同卵双生子患同病。染色体G显带分析,未见数目和结构异常,分析提示本病呈常染色体显性遗传,并结合文献对本病的发病机理进行了讨论。
In this article, we have analyzed four families with keloid history.28 people in the four families were found suffering from the disease. Among them 13 are male and 15 are female And a pair of homozygotic twins were found haying the disease at the same time. G-banding of chromosome showed no abnormality in the number and structure. The analysis indicates that keloid is a disease of autosomal dominant inheritance. The pathogenic mech- anism is also discussed.
出处
《泰山医学院学报》
CAS
1990年第4期277-279,共3页
Journal of Taishan Medical College
关键词
瘢痕疙瘩
系谱
遗传学分析
Keloid
Family pedigree
Autosomal dominant inheritance
