中华补血草的化学成分研究

Chemical constituents of Limonium sinense

目的研究中华补血草Limonium sinense全草的化学成分。方法利用萃取、制备薄层、反复硅胶、Sephadex LH-20、开放ODS柱色谱等方法进行分离纯化,根据理化常数测定及波谱分析对分离得到的化合物进行结构鉴定。结果分离得到11个化合物,分别鉴定为异鼠李素(1)、甘露醇(2)、β-谷甾醇(3)、齐墩果酸(4)、槲皮素(5)、槲皮素3-O-β-D-葡萄糖苷(6)、没食子酸乙酯(7)、山柰酚(8)、山柰酚-3-O-α-L-吡喃鼠李糖苷(9)、(+)-儿茶素(10)、异鼠李素-3-芸香糖苷(11)。结论化合物4、6、7、10、11为首次从中华补血草中分离得到。

Objective To study the chemical constituents of Limonium sinense.Methods Eleven compounds were isolated by extraction,preparation-TLC,repeat-silicagel column,Sephadex-LH20,and opened-ODS column chromatography,and identified on the basis of physicochemical constant and spectra analysis.Results Eleven compounds were isolated and their structures were identified as isorhamnetin（1）,mannitol（2）,β-sitosterol（3）,oleanolic acid（4）,quercetin（5）,quercetin-3-O-β-D-glucoside（6）,ethylgallate（7）,kaempferol（8）,kaempferol-3-O-α-L-rhamnopyranoside（9）,（＋）-catechin（10）,and isorhamnetin-3-rutinoside（11）.Conclusion Compounds 4,6,7,10,and 11 are obtained from L.sinense for the first time.