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Sonoclot分析仪在体外循环冠脉旁路移植术中的应用评价 被引量：2

Estimation of Sonoclot Analyzer in Extracorporeal Circulation Coronary Artery Bypass Grafting
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摘要 目的:用Sonoclot血小板功能分析仪监测体外循环(ECC)冠状动脉旁路移植术(CABG)中凝血功能的变化。方法:随机选择20例ECC下行CABG病人,在全麻诱导前(T1)、停机并用鱼精蛋白中和后10 min(T2)及手术结束(T3)时抽取血样,检测血小板功能和ACT、PT、APTT、Fib、TT、Hb。结果:与T1比较,T2和T3的PT、APTT、TT延长,Fib下降,ACT延长,CR、PF下降,T3与T2比较凝血时间缩短。结论:Sonoclot分析仪能够较为准确地监测ECC后凝血功能的变化。 Objective： To monitor the changes in blood coagulation with sonoclot platelet functional analyzer during extracorporeal circulation（ECC） coronary artery bypass grafting（CABG）.Methods： Twenty cases with CABG were randomly selected.Blood was taken to test platelet function,ACT,PT,APTT,Fib,TT,and Hb before induction of general anesthesia（T1）,at 10 min after protamin neutralization（T2）,and at the end of surgery（T3）.Results： Compared with those at T1,the value at T2 and T3 of PT,APTT,TT and ACT increased,CR,PF and Fib decreased.Moreover,compared with T2,coagulation time decreased at T3.Conclusion： Sonoclot analyzer can monitor the changes in coagulation function after ECC.
作者 高顺利 薛玉良 王洪武
机构地区 天津医科大学泰达心血管临床学院
出处 《包头医学院学报》 CAS 2011年第1期46-48,共3页 Journal of Baotou Medical College
关键词 血小板功能分析仪 凝血功能 体外循环 Platelet functional analyzer Coagulation function Extracorporeal circulation
分类号 R654.2 [医药卫生—外科学]
  • 相关文献

参考文献8

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二级参考文献25

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共引文献13

同被引文献24

  • 1吴志云,蔡骅,王永盛,陈建洪.Sonoclot凝血分析用于DIC的治疗[J].临床军医杂志,2005,33(3):366-367. 被引量：2
  • 2MICHAEL A, MICHAEl. T, CHRISTINE R, et al. Platelet function monitoring with the Sonoclot analy- zer after in vitro tiro.9 ban and heparin administration [J]. J Thorae Cardiovasc Surg, 2006, 131: 1314- 1322.
  • 3JONATHAN H, WATERS, DAVID G, et al. Bleeding in a patient receiving platelet aggregation inhibitors [J]. Anesth Analg, 2001,93 : 878- 882.
  • 4CAROLINE U, NILSSON, MARTIN ENGSTROM. Monitoring fondaparinux with the Sonoclot [J]. Blood Coagu[ Fibrinolysis,2007,18 : 619- 622.
  • 5MICHAEl. T, ANTOINETTE MONN, REZA TAV AKOLI,et aL Kaolin-based activated coagulation time measured by sonoclot in patients undergoing cardiop- ulmonary bypass [J ]. Journal of Cardiothoracic and Vascular Anesthesia, 2007,21 : 524- 528.
  • 6DONG Y, NUTTALL G A, OLIVER W C, et al. Aprotinin does not prolong the Sonoclot aprotinin-in- sensitive activated clotting time[J]. Journal of Clinical Anesthesia, 2007,19 ..424-428.
  • 7HILDE PLEYM, ALEXANDER WAHBA, LISE BJ- ELLA,et al. Sonoclot analysis in coronary artery sur- gery: a comparison between patients with unstable coronary artery disease treated with enoxaparin before surgery and patients with stable coronary artery dis ease not treated with enoxaparin[J]. Journal of Car- diothoracic and Vascular Anesthesia, 2008,22 .. 670 - 674.
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  • 9CASUTT M, KRISTOFFY A, SCHUEPFER G, et al. Effects on coagulation of balanced (130/0. 42) and non-balanced (130/0.4) hydroxyethyl starch or gelat- in compared with balanced Ringer's solution., an in vitro study using two different viscoelastic coagulation tests ROTEMTM and SONOCLOTTM [. British Journal of Anaesthesia, 2010,105 : 273 - 281.
  • 10VIKRAM AGGARWAL, POONAM MALHOTRA KAPOOR,MINATI CHOUDHURY, et al. Utility of Sonoclot analysis and tranexamic acid in tetralogy of Fallot patients undergoing intraeardiac repair[. An- nals of Cardiac Anaesthesia, 2012,15 .. 26- 31.

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二级引证文献3

包头医学院学报
2011年 第1期

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