腹膜后纤维化临床及影像学评价

通过分析腹膜后纤维化(RetroperitonealFibrosis,RPF)的临床及影像学表现,加深对此少见病的认识,提高早期诊断水平。RPF临床症状主要以腰背、腹痛及尿路梗阻为首发症状,常伴有以血沉(ESR)、免疫球蛋白G(IgG)、C反应蛋白(CRP)增高及肾功能异常。影像表现病变位于腹膜后,呈肿块或弥漫。CT平扫见腹膜后密度较为均匀或不均匀的软组织肿块,增强扫描显示不同程度强化;MRI在T1WI呈低信号,而在T2WI则信号强度不等。CT和MRI在RPF的诊断中起重要作用,并能进行分期及疗效监测,X线和B超对RPF的诊断起辅助作用,影像学检查结合临床表现,能提高对RPF此类少见病的诊断和鉴别诊断。

To analyze the clinical and radiological features of retroperitoneal fibrosis（RPF）,and to deepen the understanding of this unusal disease and improve the diagnostic level at the early stage.The very first symptoms usually included back pain,bellyache,or urinary tract obstruction,with increase of ESR,G（IgG）,CRP,value and abnomal renal function.The result of radiological examination showed lesions located at retroperitoneum.it were mass type or diffuse type.Non-contrast CT scanning revealed sofe tissue mass at retroperitoneum with inhomogenous or homogenous density.After contrast medium injection the lesions were enhanced with differet extent,MRI results showed that the lesions presented low signal in T1WI,while in T2WI the signals had no obvious coherence but were different from one case to another.CT and MRI play an important role in the diagnosis,staging and curative effect in the retroperitoneal fibrosis while X-ray and B-ultrasound play a subsidiary effect.Radiological examination and the primarymeans of clinical manifestations,can improve the RPF rare disease diagnosis and differential diagnosis.