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p38丝裂原活化蛋白激酶与呼吸道变应性疾病

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摘要 丝裂原活化蛋白激酶（mitogen activated protein kinase，MAPK）是生物体内重要的信号传导通路之一，p38 MAPK是MAPK家族中最重要的信号分子。在信号通路水平阻断和调控p38 MAPK的表达和活性可能成为治疗呼吸道变应性疾病的一个新途径，本文就其参与炎症反应的机制及其与呼吸道变应性疾病关系做一综述。
作者 耿娟娟 邱书奇 曾宪海 李娟娟
机构地区 遵义医学院 深圳市耳鼻咽喉研究所深圳市龙岗中心医院耳鼻咽喉头颈外科医院耳鼻咽喉科
出处 《国际耳鼻咽喉头颈外科杂志》 2011年第2期87-91,共5页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 p38丝裂原活化蛋白激酶类(p38 MITOGEN Activated Protein Kinases) 超敏反 应(Hypersensitivity) 呼吸系统(Respiratory System)
分类号 R56 [医药卫生—呼吸系统]
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参考文献20

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二级参考文献18

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国际耳鼻咽喉头颈外科杂志
2011年 第2期

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