老年患者肺部感染铜绿假单胞菌的危险因素及耐药性分析

Risk factors and antimicrobial resistance of pseudomonas aeruginosa causing pulmonary infections in senile patients

目的探讨老年患者肺部感染铜绿假单胞菌(PAE)的危险因素及耐药现状,为临床医师诊断与治疗疾病提供依据。方法细菌培养鉴定按照《全国临床检验操作规程》进行;药敏试验采用K-B法。结果老年患者肺部感染的201株PAE对亚胺培南、美罗培南、哌拉西林/他唑巴坦、头孢哌酮/舒巴坦耐药率较低,分别为1.5%、1.5%、15.4%、14.4%,耐药率>40.0%的抗菌药物有磺胺甲噁唑/甲氧苄啶、庆大霉素、氨曲南、环丙沙星、哌拉西林。结论加强医院感染管理,降低老年患者医院感染发生率。

OBJECTIVE To approach the risk factors and antimicrobial resistance of Pseudomonas aeruginosa （PAE） causing pulmonary infections in senile patients and provide the evidence for clinical diagnosis and treatment. METHODS Referring to National Guide to Clinical Laboratory Operation Procedures, the strains were cultured and identified. The susceptibility test was performed by K-B methods. RESULTS Among 201 isolates of PAE, the resistant rates to imipenem, meropenem, piperacillin/tazobactam and cefoperazone/sulbactam were the lowest, which were 1.5%, 1.5%,15.4% and 14.4%, respectively. The antibiotics to which the resistant rates were above 40. 0% comprised sulfametboxazolum trimethoprimum, gentamincin, aztreonam, ciprofloxacin and piperaciilin. CONCLUSION It suggests that nosocomial infections management should be strengthened to decrease the incidence of nosocomial infections in senile patients.