偏振控制光强调制型点阵SPR传感器研究

Intensity-Modulated Surface Plasmon Resonance Array Sensor Based on Polarization Control

介绍了一种偏振控制光强调制型点阵表面等离子体共振(SPR)传感器,分析了入射角度、金膜厚度、起偏器设置、光源波长及数据处理方式对传感器灵敏度和线性范围的影响,并对632.8 nm与740 nm两种光源传感器系统进行了实验测试与分析。结果表明,偏振控制光强调制型点阵SPR传感器可将光经过表面等离子体共振所产生的偏振态变化转化为光强变化来测量,选取适合的光源波长和入射角度,采用简单的光学结构与机械结构,就能使其获得较高的灵敏度,且测量范围控制方便,制作成本较低。偏振控制光强调制型点阵SPR传感器可广泛应用于生物分子相互作用分析和环境监测、食品安全、药物分析、生物医疗等领域的高通量检测。

Intensity-modulated surface plasmon resonance（SPR） array sensor based on polarization control is introduced.The influence of incident angle,gold firm thickness,polarizer angle,wavelength and data processing on its sensitivity and measuring range is analyzed and sensor systems with wavelength set at 632.8 nm and 740 nm are experimentally studied.It is concluded that intensity-modulated SPR array sensor turns the polarization state change of light wave during the excitation of surface plasmons into intensity change to detect in an easily controllable measurement range.Using an appropriate parameter selection,high sensitivity can be produced with a simple optical and mechanical structure and lower production costs.This scheme can be widely applied to the high-throughput detections of bimolecular interaction analysis,environmental monitoring,food safety,pharmaceutical analysis,biomedical engineering and other fields.