舒芬太尼预处理抑制无抽搐电休克中肌颤和肌痛的临床观察

Clinical Study on Sufentanil Pretreatment Reducing the Muscle Fasciculation and Myalgia Treated by Modified Electrocon vulsive Therapy

目的观察舒芬太尼预处理对精神病患者无抽搐电休克治疗肌颤和肌痛的影响。方法选择我院无抽搐电休克（MECT）患者80例随机分为对照组（n=40）和干预组（n=40）。对照组在依托咪酯配伍琥珀胆碱麻醉下行MECT。观察患者肌颤情况,自主呼吸恢复时间、苏醒时间。并记录患者睁眼的即时（T 0）、30分钟（T 1）、6小时（T 2）疼痛,视觉模糊评分（VAS）。干预组在麻醉前5分钟静脉注射舒芬太尼0.2ug/kg,其余治疗同对照组。结果两组比较,自主呼吸恢复时间,苏醒时间干预组肌颤发生率明显低于对照组。程度也明显减轻（P〈0.05）。T 1、T 2时VA S小于对照组（P〈0.05）。结论舒芬太尼预处理可有效抑制无抽搐电休克治疗中的肌颤和肌痛。

Objective To investigate the influence of sufentanil pretreatment on the muscle fasciculation and myalgia treated by modified electroconvulsive therapy（MECT）.Methods A total of 80 psychotic patients were randomly divided into two groups： control group（n=40） and treatment group（n=40）.The patients in control group were performed by MECT after anesthetizing with etomidate and succinycholine intravenously.Electroencephabgram,Awakening time,recovery time,recovery time of spontaneously breathing and adverse reactions were recored.The visual analogue scale（VAS） at T0（just after recovery）,T1（30 min after recovery） and T2（6 hours after recovery） were recored.At the same time,The patiens in treatment group were given additionnal sufentanil（0.2ug/kg）five minutes before anesthesia.Results There were no significant differences in recovery time of spontaneously breathing,awakening time and VAS between two groups（P〉0.05）.The incidence of musle fasciculation in treatment group was significantly belower than that in control group.So was the degree of muscle fasciculation（P〈0.05）.Conclusion Sufentanil pretreatment can effecively relieve the muscle fasciculation and myalgia caused by MECT.