高血压患者年龄对处方行为的影响分析

Analysis of the Effect of Age on the Prescribing Behavior of Hypertensive Patients

目的:探索不同年龄段高血压患者的处方规律,为临床治疗决策和干预提供依据。方法:对我院2009年11月-2010年10月的高血压患者的处方进行分析,统计不同年龄段(<40、40～59、60～79、≥80岁)患者的就诊次数、用药频次、联合用药情况。结果:60～79岁年龄段的高血压患者1年中就诊次数最多,其中就诊5～8次和>8次的患者分别为25.45%和36.69%。40～59、60～79和≥80岁3个年龄段的患者单药使用的比例为38.33%、40.52%、46.68%,联合2种药物使用的比例为43.01%、38.35%、35.28%,血管紧张素Ⅱ受体拮抗药(ARB)和钙离子通道阻滞药(CCB)在处方中出现的频次分别为25.21%、29.17%、31.23%和31.41%、33.54%、41.80%。结论:随着年龄的增加,单药治疗高血压的处方不断增加,联合用药治疗高血压的处方不断减少,但ARB和CCB的用药频次随年龄的增加而增加。

To explore the characteristics of prescriptions of hypertensive patients with different ages to provide reference for clinical decision and interventions. METHODS： The prescriptions of hypertensive patients in our hospital during Nov. 2009--Oct. 2010 were analyzed. The number of visiting, frequency of drug use and drug combination were analyzed according to different age groups（〈40, 40-59, 60-79, ≥80 years）. RESULTS： The highest number of one-year visiting appeared in patients aged 60-79 years. The percentage of patient to see a doctor 5-8 times per year and more than 8 times per year were 25.45% and 36.69%. For hypertensive patients of 3 age groups （40-59 years, 60-79 years, ≥-80 years）, the proportions of single-drug ther- apy and 2 drugs combination therapy were 38.33%, 40.52%, 46.68% and 43.01%, 38.35%, 35.28%, respectively. The percentage of ARB and CCB were 25.21%, 29.17%, 31.23% and 31.41%, 33.54%, 41.80%. CONCLUSION： With increasing age, single-drug therapy for hypertension increases gradually. The combination therapy for hypertension continues to decline, the frequency of prescribing ARB and CCB increase gradually.