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Livin与良性列腺增生关系的研究进展

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摘要 良性前列腺增生（benign prostatic hyperplasia，BPH）是老年男性的常见病和多发病，随着社会人口老龄化，BPH的发病率将会越来越高。凋亡抑制蛋白Livin通过改变组织细胞凋亡增殖的平衡，而在BPH的发生发展中发挥着重要作用。
作者 李鑫(综述) 曹林升(审校)
机构地区 福建医科大学附属第一医院泌尿外科
出处 《国际泌尿系统杂志》 2011年第2期195-199,共5页 International Journal of Urology and Nephrology
关键词 前列腺增生
分类号 R697.3 [医药卫生—泌尿科学]
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参考文献21

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二级参考文献17

  • 1鞠文,何远桥,杨军,肖亚军,苏昌明,曾甫清,肖传国.BPH和前列腺腺癌中Livin的表达及其意义[J].临床泌尿外科杂志,2005,20(12):762-764. 被引量：7
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  • 3Jiing-Huey Lin, Gary Deng, Qihong Huang, et al. KIAP, a Novel Member of the Inhibitor of Apotosis Protein Family. Biochemical and Biophysical Research Communications, 2000,279 (3) : 820- 831.
  • 4Ashhab Y, Allan A, Plliack A, et al. Two splicing variants of apoptosis gene with different biological properties and tissue distribution pattern. FEBS Lett, 2001,495: 56-60.
  • 5Deveraux Q L, Reed J C. IAP family proteins suppressors of apoptosis. Genes Dev,1999,13(3) : 239-252.
  • 6Germana Sanna M, Jean da Silva Correia, Odile Ducrey, et al. IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition. Mol Cell Biol, 2002, 22 (6):1754- 1766.
  • 7Schmollinger J C, Vonderheide R H, Hoar K M, et al.Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. PNAS,2003,100(6) :3398-3403.
  • 8I Crnkovic Mertens, F Hoppe-Seyler, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML IAP/KIAP gene. Oncogene,2003,22(51) : 8330-8336.
  • 9Vucic D, Deshayes K, Ackerly H, et al. SMAC Negatively regulates the Anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP). J Biol Chem, 2002,277:12275-12279.
  • 10Vucic D,Stennicke HR,Pisabarro MT,et al.MI-IAP,a novel inhibitor of apoptosis that is preferentially expressed in human melanomas[J].Curt Biol,2000;10(21):135-166.

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国际泌尿系统杂志
2011年 第2期

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