相同发育年龄的足月儿与早产儿睡眠脑电图特征对比分析

Sleep EEG features in full term and preterm neonates at matched postmenstrual ages

研究了振幅整合脑电图（aEEG）和样本熵评价新生儿脑发育成熟度是否受到胎龄的影响,计算了210例足月儿和122例早产儿在活动睡眠和安静睡眠（QS）阶段的aEEG和样本熵。结果表明：对于相同受孕后年龄（PMA）的足月儿和早产儿,其振幅整合脑电图的上、下边缘幅度值没有统计学差异;PMA在37~42周的QS阶段,足月儿的脑电样本熵明显高于早产儿（p〈0.01）,其他PMA阶段样本熵在足月儿与早产儿间无统计学差异。aEEG脑发育特征随PMA改变;样本熵特征则受到胎龄影响。

To explore whether gestational age affects evaluations of neonatal cerebral development when using amplitude-integrated electroencephalography（aEEG） and sample entropy,the aEEG and sample entropy were calculated during active sleep and quiet sleep with 210 full term and 122 preterm neonates.The results show that there was no significant difference in the upper/lower margin of the aEEG and sample entropy between the full term and preterm neonates at matched postmenstrual ages,except for the sample entropy during quiet sleep in the group of 37 and 41 weeks（p0.01）.Although the aEEG changes with ages,the gestational age should be taken into consideration when the sample entropy is applied to maturation evaluation.