基于GATE程序的MicroPET系统设计Monte Carlo模拟验证

Monte Carlo simulation using GATE to verify the MicroPET system design

MicroPET是专用于小动物成像的分子核医学成像设备。该文使用Monte Carlo程序GATE,模拟了MicroPET成像系统整环探测器结构,对探测器晶体结构进行了比较精确的建模,实现了γ光子在体模内和整环探测器上硅酸镥(LSO)晶体内输运过程的模拟。通过实验室计算机集群GATE程序的并行化模拟,提高了模拟效率,获得了点源、线源、圆柱源、Derenzo模型的投影数据以及系统传输矩阵,并重建获得了断层图像。模拟结果验证了该MicroPET系统的设计。

MicroPET（small animal positron emission tomography） is a dedicated molecular imaging device for small animal imaging.A Monte Carlo simulation program was used to simulate the entire ring detector of a MicroPET system using the GATE program.The crystal model structure of the detector was more precisely modeled with a simulation of the γ photon transport in the phantom and the Lu2（SiO4）O（LSO） crystal.The simulation efficiency was greatly improved through parallel computing to obtain projection data for various sources,including a point source,a line source,a cylindrical source,and a Derenzo phantom.The system transfer matrix was determined and used to reconstruct slice images using the output data.The simulation results verify the MicroPET system design.