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尿路上皮癌中FGFR3基因的研究进展

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摘要 成纤维细胞生长因子受体3(FGFR3)是跨膜的酪氨酸蛋白激酶受体家族成员之一,近年大量的研究表明,FGFR3基因的突变与病理分级、临床分期低的尿路上皮癌有密切的相关性,有可能成为对尿路上皮癌诊断、进行监测随访的分子标志物和治疗的靶点。本文就FGFR3基因在尿路上皮癌中作用的研究进展作一综述。
作者 梁宇 刘久华
出处 《癌变.畸变.突变》 CAS CSCD 2011年第1期72-74,77,共4页 Carcinogenesis,Teratogenesis & Mutagenesis
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