支气管哮喘中医证候演变规律的调查研究

Investigation Study of TCM Syndromes Evolution Law of Bronchial Asthma

目的探讨支气管哮喘中医证候特点,并分析缓解期与发作期证候的演变规律。方法采用临床流行病学方法对哮喘证候开展前瞻性调查研究,按照现有哮喘证候诊断标准,遵循循证医学原则,应用Epi da-ta3.0建立数据库,将符合纳入标准的哮喘患者的四诊信息进行二次录入核对,运用SPSS13.0统计软件对证候及证候要素进行频次分析。结果哮喘发作期证候类型以热哮、风哮为主,病位主要涉及肺、脾、肝,病性以气郁、痰阻多见;哮喘缓解期脾气亏虚最多,且往往兼夹两种甚至多种脏腑亏虚症状,并与发作期证候有一定关系;哮喘患者随年龄增长,病性表现从风哮、热哮到冷哮、虚哮和病位从肺及脾至肾的由轻到重的演变规律。结论了解哮喘发作期与缓解期证候特点及演变规律,将有助于哮喘的防治。

Objective：To study the characters of TCM syndrome with bronchial asthma and to analyse the distribution and evolution law of TCM syndromes of during attack and remission stage.Methods：According to present diagnostic criteria of syndromes of asthma,a prospective investigation was carried out in the way of clinical epidemiology.Based on the principle of evidence-based medicine,the database including enrolled patients＇ informations collected with four TCM diagnostic methods was established with SPSS13.0 statistical software for their syndrome and symptoms.Results：The most frequent syndrome of asthma were heat syndrome and wind syndrome.Their locations were lung,spleen and liver.The natures of disease were chiefly the depressed vital energy and the stagnation of phlegm.In the remission,the most syndrome was the spleen deficiency.In this period,there was usually two or even folders and multiple organs with deficiency symptoms,and there was a certain relationship between attack and remission stage.With age increase,it was getting worse,from wind and heat syndrome to cold and deficiency,or from lung to spleen or kidney.Conclusion：Understanding the evolution law about asthma during attack and remission stage will help control asthma.