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7例危重症H1N1甲型流感肺炎患者的临床特征与治疗

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摘要 目的:总结危重症H1N1甲型流感肺炎患者的主要临床特点,探索临床有效的治疗方法及机械通气在危重症患者抢救中的作用。方法:回顾性分析入住本院重症监护室及呼吸科的7例危重症H1N1甲型流感肺炎患者的临床资料和治疗方法。结果:7例患者中孕产妇、有慢性基础病者6例;进行性呼吸困难、咳嗽、痰中带血是主要症状,双肺多发实变影6例(85.71%)。血清中乳酸脱氢酶(LDH)平均值为(1 857.29±3 613.86)U/L,血清白蛋白平均值为(30.44±4.56)g/L。7例患者均用抗病毒治疗(奥司他韦剂量150 mg/次,2次/d),全部用激素及抗感染、气管插管机械通气治疗,死亡1例,病死率14.29%。结论:血清中LDH升高、白蛋白降低是危重症H1N1甲型流感肺炎患者预后不佳的预测指标;早期有创机械通气支持治疗对于肺内广泛实变者效果理想,有助于提高抢救成功率。
出处 《天津药学》 2011年第1期31-34,共4页 Tianjin Pharmacy
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  • 1Jain S, Kamimoto L, Bramley A M ,et al. Hospitalized Patients with2009 HIN1 Influenza in the United States, April- June 2009. N Engl J Med, 2009,361(11) :1935.
  • 2Centers for Disease Control and Prevention (CDC). 2009 pandemic influ- enzaA (H1N1) virus infections - Chicago, Illinois, April - July 2009. MMWR Morb Mortal Wkly Rep,2009,58 ( 33 ) :913.
  • 3Chowell G, Bertozzi S M, Colchero M A,et al. Severe respiratory diseaseconcurrent with the circulation of H1N1 influenza. N Engl J Med,2009, 361 (7) :674.
  • 4Perez - Padilla R , de la Rosa - Zamboni D, Ponce de, et al. Pneumonia and respiratory failure from swine - origin influenza A ( H1N1 ) in Mexico. N Engl J Med,2009,361 (7) :680.
  • 5王军,于岩岩,聂立功.40例重症SARS患者乳酸脱氢酶的变化与预后[J].实用心脑肺血管病杂志,2006,14(8):651-652. 被引量:2
  • 6Bishop J F, Mumane M P, Owen R. Australia' s winter with the 2009 pandemic influenza A (H1N1) virus . N Engl J Med, 2009,361(27) : 2591.
  • 7Perez Padilla R , de la Rosa Zamboni D, Ponce de, et al. Pneumonia and respiratory failure from swine- origin influenza A (H1N1) in Mexico. N Engl J Med,2009,361 (7) :680.
  • 8Centers for Disease Control and Prevention (CDC). Intensive - care patients with severe novel influenza A (H1N1) virus infection - Michigan, June 2009. MMWR Morb Mortal Wkly Rep,2009, 58(27) :749.
  • 9Dawood FS , Jain S , Finelli L, et al. Emergence of a novel swine - origin influenza A (H1N1) virus in humans. N Engl J Med, 2009, 360(25) : 2605.

二级参考文献6

  • 1田晓清.SARS临床诊治现状--钟南山[N].中国医学论坛报,April 29,2003.
  • 2中华人民共和国卫生部办公厅.传染性非典型肺炎临床诊断标准(试行)[S].中国疾病预防控制中心.传染性非典型肺炎(SARS)防治技术与综合管理[C].北京:中国协和医科大学出版社,2003.30-31.
  • 3Booth CM,Matukas LM,Tomlinson GA,et al.Clinical features and short-term outcomes of 144 patients with SARS in the Greater Toronto Area[J].JAMA,2003,289:1-9.
  • 4Nelson Lee,David Hui.A major outbreak of severe acute respiratory syndrome in Hong Kong[J].N Engl J Med,2003,348:1995-2005.
  • 5JS M Peiris,CM Chu,VC Cheng,et al.Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia:a prospective stuty[J].Lancet,2003,361:1767-1772.
  • 6何为群,陈思蓓,刘晓青,黎毅敏,萧正伦,钟南山.SARS合并ARDS患者死亡高危因素分析[J].中国危重病急救医学,2003,15(6):336-337. 被引量:32

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