HBsAg携带者乙肝血清学标志物模式分析

目的了解人群中男性、女性的HBsAg携带率和乙肝血清学标志物模式。方法从健康体检人员30823人筛选出HBsAg携带者1913人,用ELISA法进行乙肝血清学标志物检测,男女携带者根据年龄分组进行统计处理,对男性、女性HBsAg携带率进行x2检验。结果经x2检验,男性HBsAg携带率(6.44%)高于女性(5.13%),P<0.005,x2=13.31;作为常见模式"135"(HBsAg、HBeAg、抗-HBc阳性)、"145"(HBsAg、抗-HBe、抗-HBc阳性)、"15"(HBsAg、抗-HBc阳性)所占百分比为9.3%、65.6%、23.6%;男、女HBsAg携带者30～39岁年龄组乙肝"135"模式比例均高于其他年龄组。结论人群中男性、女性在HBV感染后的转归有所不同;各年龄段HBsAg携带者均以乙肝"145"模式为主。

Objective To analyze the distribution of HBV serological markers and proportion of positive HBsAg in different sex groups. Methods HBV serological markers of HBsAg carriers 1913 person obtained from physical examination personnel 30823 persons were detected by ELISA. Results Male HBsAg carrying rate （6.44%） is higher than female （5.13%） （P0.005, x2=13.31）; for convenience, we set the numbers 1 2 3 4 and 5 to represent HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc respectively. The percentage of common models ‘135’, ‘145’ and‘1 5’ were 9.3%, 65.6%, 23.6% Among HBsAg carriers in age group 30-39, the proportion of HBV ‘135’ model were higher than other age groups. Conclusion The outcome between men and women after HBV infection were different. Each age range of HBsAg carriers were ‘ 145’ model primarily.