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LT_4治疗妊娠期甲状腺功能不足效果观察 被引量:3

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摘要 目的观察左旋甲状腺素(LT4)治疗妊娠期甲状腺功能减退(甲减)的效果。方法以筛查出的35例妊娠期临床/亚临床甲减孕妇中愿意接受LT4治疗的22例患者为观察组,均给予LT4口服,每4周复查血清TSH、FT4水平,及时调整服用剂量至TSH达到正常水平,直至分娩;其余13例不愿接受治疗的13例患者为对照组。随访观察妊娠结局及新生儿情况。结果观察组发生妊娠并发症1例(4.5%),对照组发生5例(38.5%),观察组新生并发症发生率显著低于对照组(P<0.05)。两组新生儿出生体质量、Apgar评分及新生儿TSH水平相比P均>0.05。结论 LT4治疗妊娠期甲状腺功能不足效果满意。
出处 《山东医药》 CAS 北大核心 2011年第6期50-51,共2页 Shandong Medical Journal
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