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胃癌组织中EGFR的表达变化及意义 被引量:4

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摘要 目的观察胃癌组织中EGFR的表达变化,并探讨其意义。方法采用免疫组化法检测45例胃癌患者肿瘤组织及20例胃黏膜正常者胃黏膜组织中的EGFR。结果胃癌原发灶中EGFR阳性表达率为63.1%,正常胃黏膜中为16%,胃癌组织中EGFR阳性表达率明显高于正常胃黏膜(P<0.05)。胃癌组织中EGFR表达与胃癌淋巴结转移程度相关(P<0.05)。结论胃癌组织中EGFR表达升高。检测胃癌组织中EGFR表达可能有助于预测胃癌淋巴结转移。
作者 邸旭
出处 《山东医药》 CAS 北大核心 2011年第6期66-67,共2页 Shandong Medical Journal
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