摘要
创伤修复是一个复杂过程,氧化应激是其重要影响因素之一,当自由基产生过多或清除能力下降时,导致氧化应激,造成创面愈合困难或延迟。根据抗氧化剂作用环节的不同,可以分为:抑制超氧阴离子的产生、促进超氧阴离子向过氧化氢转化、促进过氧化氢代谢、清除已生成的自由基四种类型的抗氧化剂。这些抗氧化剂都有减轻氧化应激,促进创伤修复的作用。
Wound healing is a complex process,in which oxidative stress is an important impact factor.When free radicals are massively generated or have the elimination decreased,oxidative stress occurs,leading to wound healing difficulty or delay.Based on their working links,anti-oxidants are divided into four groups,namely,inhibiting the generation of superoxide anion,promoting the conversion of superoxide anion to hydrogen peroxide,enhancing hydrogen peroxide′s metabolism,and eliminating already generated free radical.Researchers suggest that the application of anti-oxidants will alleviate oxidative stress and accelerate wound healing.
出处
《医学综述》
2011年第4期498-500,共3页
Medical Recapitulate
关键词
创伤修复
氧化应激反应
活性氧
活性氮
抗氧化剂
Wound healing
Oxidative stress
Reactive oxygen species
Reactive nitrogen species
Anti-oxidant
