原发性腹膜后肿瘤46例诊疗分析

Diagnosis and Treatment Analysis on 46 Cases of Primary Retroperitoneal Tumor

目的:总结并探讨原发性腹膜后肿瘤(PRPT)的诊断及治疗方法。方法:回顾并分析2004年1月至2009年12月收治的46例腹膜后肿瘤患者的临床资料及随访结果。结果:良性肿瘤17例,完整切除15例,部分切除2例,复发4例,均再次手术;恶性肿瘤29例,完整切除10例,部分切除15例,活检2例,复发6例,再次手术4例。随访时间0.5至5年,良性肿瘤死于其他疾病3例,死于原发性腹膜后肿瘤1例;恶性肿瘤死亡22例,其中1年内死亡8例,3年内死亡12例,5年内死亡2例。结论:对原发性腹膜后肿瘤,B超、CT及MRI检查是目前诊断PRPT方便、有效的诊断手段,手术治疗是治疗PRPT的首选治疗方式,完整切除肿瘤是影响PRPT治疗效果及其预后的重要因素。对于复发病例应选择再次手术治疗。

Objective：To summarize and review our experience on the diagnosis and treatment of primary retroperitoneal tumor（PRPT）.Methods：The clinical data of 46 patients with PRPT（from Jan.2004 to Dec.2009） were retrospectively analyzed,and the clini-cal experience on diagnosis,treatment and follow-up survey were summarized.Results：There were 17 cases of benign tumor and 29 cases of malignant tumor in all the cases.15 cases of benign PRPT and 10 cases of malignant PRPT underwent complete resection.2 cases of benign PRPT along with 15 cases of malignant PRPT underwent partial resection.All 4 cases of recurrent benign PRPT underwent sec-ond resection,as well as 4 cases of 6 cases who suffered from recurrent malignant PRPT.The follow-up survey lasted 0.5 to 5 years.1 patient of benign PRPT died on PRPT and 3 patients died on other diseases.Besides 8 patients of malignant PRPT who died within 1 year,12 and 2 patients of malignant PRPT respectively died within 3 and 5 years.Conclusion：Ultrasound examination and imaging diag-nosis can conveniently and effectively identify PRPT.Surgical treatment is the first choice for PRPT.Complete resection is a key factor in curing PRPT.Patients with recurrent PRPT should receive second operation.