芦笋皂苷的抗肿瘤作用研究进展

Research Advancement on Anti-tumor Activity of Saponins from Asparagus officinalis L.

芦笋是一种常见蔬菜,富含多种营养物质,在多种疾病的预防和治疗中发挥良好的药理效应。芦笋中的甾体皂苷是其生物活性的主要表现物质,现已从芦笋中分离出的皂苷单体有19种。本文概述了它们的来源及结构,对其中已被报道的几种皂苷单体在肿瘤预防和治疗方面的作用、机理及研究进展加以综述,为进一步分离新的芦笋皂苷单体及其对肿瘤的预防和治疗提供参考。

Asparagus officinalis L.is a common green vegetable,rich in a variety of nutrients,and possesses pharmacological effects on the prevention and treatment of several diseases.The saponins are the main active component of Asparagus officinalis L.and performance of potential biological actions.This paper has outlined 19 saponin monomers separated from Asparagus and summarized their anti-tumor functions and corresponding mechanism,which may serve as a reference for further researches.