补心气口服液对慢性稳定型心绞痛患者生活质量影响及疗效观察

Effects of Buxinqi on quality of life and treatment for coronary artery disease patients with stable angina pectoris

目的:观察中药补心气口服液治疗慢性稳定型心绞痛的疗效及其对患者生活质量的影响。方法:将63例经冠状动脉造影确诊为稳定型心绞痛的患者随机分为2组:补心气口服液组,给服补心气口服液10 ml,tid;硝酸酯类组,给服硝酸异山梨酯10 mg,tid或单硝酸异山梨酯20 mg,bid;治疗12周后,比较2组疗效,并采用西雅图心绞痛调查问卷(SAQ)生活质量测定量表,评价2组治疗后生活质量改善的情况。结果:2组心电图疗效比较,差异无统计学意义(P>0.05),在改善临床症状和生活质量方面,补心气口服液组明显优于硝酸酯类组(P<0.05)。结论:补心气口服液能有效改善心肌缺血和临床症状,并能提高患者的生活质量。

Objective：To observe the effects of Buxinqi on quality of life and treatment for coronary heart disease（CHD） patients with stable angina pectoris（SAP）.Method：A total of 63 CHD subjects with SAP diagnosed by coronary artery angiography（CAG） were divided into two groups.Patients were given Buxinqi 10 ml tid in research group（n=32） and Isosorbide Dinitrate10 mg tid or Isosorbide Mononitrate 20 mg bid in control group（n=31） for 12 weeks,respectively.SAQ（Seatle Angina Questionaire） was adopted in studying quality of life before and after treatment in these patients.Result：There was no significant difference in the changes of electrocardiogram（ECG） between the two groups（P0.05）.Improvement of angina and quality of life in research group were much better than those in control group（P0.05）.Conclusion：Buxinqi can significantly improve angina and quality of life in CHD patients with SAP.