福建省医院感染横断面调查结果趋势分析

Cross-sectional survey on nosocomial infection in Fujian

目的评价福建省医院感染横断面调查结果的趋势变化。方法对2007、2009年两次福建省医院感染横断面调查结果相关指标进行分析。结果 2007年医院感染现患率为3.66%,2009年为3.26%,差异有统计学意义(P<0.01);两次调查中医院感染现患率前5位科室及主要病原菌无明显变化,分别以综合ICU和铜绿假单胞菌最高;手术部位感染现患率由2007年的0.35%下降至2009年的0.25%(P=0.011);其他部位感染现患率则差异无统计学意义;医院感染病原菌以革兰阴性菌为主;抗菌药物使用率由39.22%降至38.28%(P=0.006),其中预防用药比例由41.14%下降至40.79%,治疗用药比例则相应提高,差异有统计学意义(P<0.01),一联用药比例由63.82%提高至67.38%,多联用药有所下降,差异有统计学意义(P<0.01);使用抗菌药物进行治疗前病原学送检率由35.77%提高至42.68%,差异有统计学意义(P<0.01)。结论福建省医院感染控制及抗菌药物管理工作取得了良好的成效。

OBJECTIVE To evaluate the tendency of the cross-sectional survey in hospital-acquired infections at Fujian Province Hospital.METHODS The results of the cross-sectional survey on hospital-acquired infections conducted in the years 2007 and 2009 were compared and analyzed.RESULTS The prevalence rate of hospital-acquired infections（HAIs） was 3.66% in 2007,which had significant difference compared with that of 2009（3.21%）（P=0.002）.The two investigations showed no significant change in the prevalence rate of HAI with regard to major pathogens and hospital departments.The prevalence rate of infection in surgical sites dropped from 0.35% to 0.25（P=0.011）;There was no significant difference in infection prevalence rate at non-surgically sites（P〉0.05）.The usage rate of antimicrobial agents dropped from 39.22% to 38.28（P=0.006）;A decrease in antibiotic usage was noted for active treatment,also in a preventive regimen（P〈0.001）.The constituent ratio for single antimicrobial usage increased from 63.82% to 67.38%,while the constituent ratio for antimicrobial combined usage dropped（P〈0.001）.CONCLUSION The considerable progress has been made with regard to management of hospital-acquired infections and antimicrobial agents in Fujian province.