眼科住院患者合并医院感染的临床特征分析

Clinical features of inpatients with combined nosocomial infection in department of orphthalmology

目的探讨眼科住院患者医院感染的特征。方法回顾性分析42例患者的临床资料,观察发生医院感染部位、病原菌检查结果;同时按照1∶1比较随机选择同期住院的无医院感染的眼科患者进行对照研究,比较两组患者医院感染相关因素的差异。结果 42例医院感染部位:急性结膜炎18例,眼内炎12例,呼吸系统感染6例,手术切口感染4例、消化系统感染2例;送检等标本32例,检出病原菌23株,革兰阳性球菌11株、革兰阴性杆菌8株、真菌4株;医院感染组平均年龄大?合并其他疾病及预防应用抗菌药物比例高、住院时间长、侵入性治疗多,差异有统计学意义(P<0.05)。结论眼科住院患者常合并医院感染,难以完全避免,应根据其临床特征实施针对性预防措施。

OBJECTIVE To explore the characteristics of nosocomial infection of the inpatients in department of orphthalmology.METHODS A total of 42 patients＇clinical data was retrospectively analyzed and the clinical data with the affected parts of the family and the pathogen outcomes were observed;at the same time,as a random choice1∶1 was the same period in hospital without an eye infection of the family of the people and study,two groups of the patient the hospital with the relevant factors differences.RESULTS Totally 42 patients were with nosocomial infection site：18 cases of acute conjunctivitis,endophthalmitis in 12 cases of respiratory infections 6 cases,surgical incision infection 4 cases,digestive system infection in 2 cases.23 strains of pathogenic microorganisms were detected from 32 cases of specimens,Gram-positive cocci 11 cases,Gram-negative bacilli 8 cases,fungi 4 cases.The nosocomial infection group had the clinical features,including the higher average age,combination with other diseases and higher proportion of prophylactic antibiotics,longer hospital stay and more invasive operation,the differences were statistically significant（P〈0.05）.CONCLUSION The inpatients from department of orphthalmology are always combined with nosocomial infection and can not be completely avoided.It should adopt preventive measures in accordance with the clinical characteristics.