有机高分子抗菌剂的制备及抗菌机理

Preparation and Antimicrobial Mechanism of Organic Polymeric Biocides

综述了有机高分子抗菌剂的研究进展,分别对带有季铵盐、季鏻盐、有机锡、吡啶类、胍盐类、卤代胺类和壳聚糖衍生物类七种抗菌基团的有机高分子抗菌剂的合成及应用等方面作了评述,重点介绍了季铵盐与季鏻盐两种有机高分子抗菌剂的发展情况,对季铵盐和季鏻盐应用于抗菌剂领域的优劣进行了比较。介绍了近几年发展较快的几种有机高分子抗菌剂的制备方法和抗菌机理,并对高分子抗菌剂的发展趋势做出了展望,指出提高抗菌性能和稳定性将是今后研究的热点。

Advance in organic polymeric biocides was reviewed in this paper. Biocides with different antibacterial functional groups, such as quaternary ammonium salts, quaternary phosphonium salts, organotin, pyridine, guanidine, N-halamines, and chitosan derivatives, their synthesis and application were described respectively. The development of quaternary ammonium salts and quaternary phosphonium salts polymeric biocides was introduced in detail, and their advantage and disadvantage were compared. The preparation and antimicrobial mechanism of several organic polymeric biocides which had been developed rapidly in recent years were introduced. Meanwhile, the foreground of the development trend of polymeric biocides was also discussed. The improvement of antimicrobial performance and stability of biocides would be main point of polymeric biocides in the future.