蒙药孟根-乌苏-18中汞含量及溶出特性研究＆

Researchs of extract mercury content and dispersive characteristics in Mongolian medicine Menggen-Wusu-18

目的:用不同介质提取,分析蒙药孟根-乌苏-18中汞含量和溶出特性。方法:实验采用双光数显测汞仪分别测定原蒙药、提取液以及悬浮态中的汞含量。结果:孟根-乌苏-18中汞的总含量为6.385 mg·g-1,远远超出国家标准(0.0002 mg·g-1),但溶出率很低,二次蒸馏水中溶出率在0.003%～0.005%之间,模拟胃液中溶出率在0.006%～0.009%之间。本方法的线性范围在0～10 ng·mL-1,RSD=3.45%,加标回收率在90.2%～93.7%之间。结论:本方法可以测定蒙药复方中的汞含量,方法简便、可行、重复性和稳定性较好,结果显示两种介质中的溶出率都在0.003%～0.009%之间。

Objective：Took the different mediums to analyze extract mercury content and dispersive characteristics from Menggen - Wusu - 18. Methods： Mensurated the technical product of pesticides extracting solution arid the mercury content in seston by Dual - SG921 significant mercury analyzer. Results ： total mercury content was 6. 385 mg ·L^-1 g m Menggen - Wusu - 18, it was far beyond the National Standard （0. 0002 mg · g^-1 ）. But, extract ratio is very low, which are between 0. 003 % -0. 005 % in second distilled water, and are between 0. 006% -0. 009 % in simulation gastric juice. This methods＇ range of linearity is between 0 - 10 ng · mL ~, relative standard deviation;RSD = 3.45% ,the recovery rate of peat is between 90. 2% and 93.7%. Conclusion：Use this method to mensurate the mercury contents in Mongolian medication compounds which is handy ,feasible and also has repetitiveness and very nice stability. The results showed that the extract ratios were very low,and between 0. 003% -0. 009%.