甘肃省临夏回族自治州应急补碘改善特需人群碘营养效果评价

Effects of iodine oil intervention for IDD vulnerable population in Gansu muslim prefecture

目的评价穆斯林民族地区特需人群补碘干预措施效果。方法采用分层抽样方法,测定补碘前的居民户盐碘,对比补碘前后特需人群(孕妇、乳母、育龄妇女、0～3岁婴幼儿)的尿碘结果。结果对孕妇、哺乳期妇女100 mg/次、育龄妇女200 mg/次、0～3岁婴幼儿20 mg/次,2次/年的剂量进行碘油补服,补服碘油后4组人群总体尿碘中位数均达到150μg/L的推荐标准,尿碘频数颁布<100μg/L的比例为21.0%,<50μg/L的比例为7.4%,>800μg/L以上的人群仅占0.3%,补碘前后尿碘水平有显著性差异。但在县级水平上,有4个县的孕妇和乳母的尿碘中位数<150μg/L。结论在碘盐未完全落实的少数民族地区,按照上述规定的剂量和时间给特需人群补服碘油,尿碘达到了碘适宜水平,未出现高碘及不良反应情况,是安全有效的补碘方法,但应进一步开展孕妇和乳母个体碘代谢相关因素的研究。

Objective To assess the effects of iodine supplement for IDD target population in muslim prefecture.Methods Iodine levels in salt and urine samples randomly collected from local pregnant women,lactation samples,child-bearing age women,and 0 to 3 years old infants were tested respectively during before and after iodine supplement.Results After 1 year intervention,it was a safe way to supply iodine for child-bearing age women,pregnant women,lactation samples and 0 to 3 years old according to the dosage of 400 mg,200 mg,200 mg and 40 mg per year respectively,the median of urine iodine among 4 groups of objects were all about 150 μg/L.The percentage of urine iodine level below 100 μg/L and 50μg/L among the target population was 21.0% and 7.4% respectively,but the median of urine iodine among pregnant women and lactation samples were below 150 μg/L in 4 counties.Conclusions After iodine supplement,the urine iodine concentration of the target population achieved the criteria of IDD elimination,indicating that iodine oil supply was a safe and effective way to improve the population quality in special regions and special population.The It was necessary to explore the median of urine iodine still under 150 μg/L among target population in national autonomous rural areas.