玉米赤霉烯酮生物合成和降解的研究进展

Research Advancement on Biosynthesis and Degradation of Zearalenone

介绍了玉米赤霉烯酮及其6个衍生物的分子结构,以及玉米赤霉烯酮的生物合成途径。阐述了玉米赤霉烯酮生物合成的基因序列群以及基因簇的表达方式。论述了玉米赤霉烯酮钝化和降解过程,探讨了玉米赤霉烯酮水解酶在基因工程中的应用研究,并为今后玉米赤霉烯酮生物工程降解研究提出了建议。

After zearalenone （ZON） and its six derivatives are introduced, its biosynthesis pathway is described. Genetic organization of ZON biosynthetic gene cluster is not only depicted but expression style of the gene cluster is illuminated as well. It is discussed how inactivation and degradation of ZON occurs. Application of ZON hydrolase on genetic engineering is summarized and several proposals for ZON degradation with biotechnology in future arc also put forward.