不同锌源和水平对奶山羊相关激素分泌的影响

Effects of Different Source and Level of Zinc on the Related Hormones in Dairy Goats

为了研究不同锌源和水平对奶山羊激素分泌的影响,本研究选择12只2.5~3岁奶山羊从瘤胃瘘管灌注不同水平的硫酸锌（ZnSO4）和氨基酸锌（Zn-AA）,颈静脉采血通过放免法测定血清中生长激素（GH）、胰岛素样生长因子Ⅰ（IGF-Ⅰ）、雌二醇（E2）、催乳素（PRL）水平。结果表明,不同锌源和水平对奶山羊激素分泌有一定影响,GH、E2随锌水平的升高而升高,PRL随锌水平的升高而降低,不同锌源之间变化趋势基本一致;IGF-Ⅰ因锌源和水平的变化而不同,ZnSO4组IGF-Ⅰ随锌水平的升高而降低,Zn-AA组IGF-Ⅰ随锌水平的升高呈先下降后升高的变化趋势。因此,不同锌源和水平均可以促进GH和E2的分泌,高锌抑制PRL的分泌,不同形式的锌对IGF-Ⅰ水平影响不同,ZnSO4抑制IGF-Ⅰ的分泌;Zn-AA在低浓度时抑制其分泌,高浓度时促进分泌。

In order to research the effect of different source and levels of zinc on the related hormone in dairy goats,12 diary goats of 2.5 to 3 years old were elected and randomly divided into 2 groups averagely,which infused different source of zinc.One group infused with different level of ZnSO4,the others infused with different level Zn-AA,the concentration of different zinc source as follows：0,20,40,60,80,100,200 mg/kg.Each infusing period were lasted 7 d.In the later 3 days,blood samples were collected from jugular and made serum to detect the zinc level and the related hormones of GH,E2,PRL and IGF-I.The results showed that the hormones had a strong relationship with the zinc source.The level of GH and E2 was increasing with the concentration of zinc.The level of PRL was decreased with the increasing of the zinc concentration.While the level of IGF-Ⅰwas decreased with the increasing of zinc concentration in the group of ZnSO4,in the group of Zn-AA,IGF-Ⅰwas decreased at lower concentration but increasing at the higher concentration.It was concluded that different source and level zinc had a promotion effect on the secretion of GH and E2,and had an inhibition effect on PRL;ZnSO4 have an inhibition effect on IGF-Ⅰ,Zn-AA inhibited IGF-Ⅰin low concentration and increased at the high level.