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RNA干扰技术在动物繁殖中的应用

Application of RNA Interference in Animal Breeding
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摘要 RNA干扰(RNA interference,RNAi)是一种由双链RNA诱发的转录后水平的基因沉默现象,是近几年发展起来的基因表达调节新机制,广泛地存在于真菌、植物和动物中。到目前为止,已有很多试验证明,RNAi作为一种基因功能研究的新手段,在动物繁殖研究中发挥了极其高效的作用。作者主要介绍了RNAi的研究历史、分子机制、作用特点、生物学意义及在动物繁殖中的应用。 RNA interference（RNAi） is a phenomenon of post-transcript gene silencing induced by double strand RNA and a new mechanism of regulating gene expressing,which widely exists in epiphyte,plants and animals.So far,a number of tests have proved that RNAi as a new method to study gene function has played a very effective role in studying of animal breeding.This study aimed to introduce the discovery of RNA interference,molecular mechanism,role of the characteristics,the significance of biology and wide application of RNAi in animal breeding.
作者 陈娟 杨永梅 陈洋 姜怀志 杨雨江 巩俊明
机构地区 吉林农业大学动物科技学院 吉林省双辽市畜牧总站
出处 《中国畜牧兽医》 CAS 北大核心 2011年第3期128-131,共4页 China Animal Husbandry & Veterinary Medicine
基金 国家自然基金项目资助(30871792)
关键词 RNA干扰 双链RNA 小干扰RNA 动物繁殖 RNA interference double strand RNA small interfering RNA animal breeding
分类号 Q75 [生物学—分子生物学]
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中国畜牧兽医
2011年 第3期

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