铁与脂质代谢关系的研究进展

Progress of Studies on Relationship between Iron and Lipid Metabolism

近年来,机体内铁稳态失调影响脂质代谢,从而影响血脂水平成为研究热点。作为生物代谢过程中大部分酶的辅助因子,铁参与机体内各种代谢过程以及氧气和电子的运输,因此铁缺乏或过量都可引发各种疾病。本综述分别从铁缺乏和超载两方面如何影响脂质代谢进行综述报道。

In recent years,the blood lipid level disturbance resulted from affected lipid metabolism by body iron homeostasis disorders became a research hotspot.As a critical cofactor of many redox enzymes,iron involved in a wide range of biological processes,as well as in oxygen and electron transportation.Lack of iron or excess of iron can result in many diseases.The effects of iron deficiency and iron overload on lipid metabolism were summarized here.