Onyx-18栓塞治疗脑动静脉畸形28例临床分析

Embolization treatment of cerebral arteriovenous malformations with Onyx-18:a clinical analysis

目的介绍应用Onyx-18栓塞治疗脑动静脉畸形的体会。方法采用Onyx-18对28例脑动静脉畸形患者进行栓塞治疗。结果 28例患者中,畸形血管团栓塞80%以上4例,其中2例达到影像学完全栓塞(血管造影动、静脉期均无畸形血管团显影),栓塞范围50%～80%20例,50%以下4例。28例中5例患者于术中或术后出现并发症,包括颅内出血3例,粘管1例,继发性癫痫1例。结论 Onyx-18是目前治疗脑动静脉畸形较理想的栓塞材料,栓塞效果确切,但需掌握栓塞技巧,减少并发症的发生。

Objective To summarize the experience of using Onyx-18 embolization for the treatment of cerebral arteriovenous malformations.Methods Interventional embolization with Onyx-18 was carried out in 28 patients with cranial arteriovenous malformations.The clinical data and the therapeutic results were analyzed.The complications were observed.Results Of the 28 patients,the embolization degree of vascular malformations 80% was achieved in 4（total occlusion was obtained in 2 cases）,50%-80% in 20,and 50% in 4.During or after the procedure five patients developed complications,including intracranial hemorrhage（n = 3）,clay pipe（n = 1） and secondary epilepsy（n = 1）.Conclusion Onyx-18 is an ideal embolization material for the treatment of cerebral arteriovenous malformations.To avoid the occurrence of complications the manipulative experience and skills are essentially required.