2型糖尿病合并非酒精性脂肪肝临床分析

Clinical analysis of non-alcoholic fatty liver combined with diabetes type II

目的:研究2型糖尿病合并非酒精性脂肪肝的危险因素及其与代谢综合征的关系。方法:将2型糖尿病患者分为2型糖尿病合并非酒精性脂肪肝组(A组)和单纯2型糖尿病组(B组)。然后对其体质量指数(BMI)、收缩压(SBP)、舒张压(DBP)、糖化血红蛋白(HbA1C)、总胆固醇(TC)、低密度胆固醇(LDL)、三酰甘油(TG)、谷丙转氨酶(ALT)、谷草转氨酶(AST)和γ-谷氨酰转移酶(GGT)等临床资料进行分析比较。结果:两组之间性别、年龄、病程差别无统计学意义(P>0.05)。脂肪肝组与无脂肪肝组T2DM患者FBG、2hBG、HbA1C、LDL-C差异无统计学意义(P>0.05);脂肪肝组较无脂肪肝组ISI、HDL-C降低;TC、TG、FINS、2hiNS、BMI升高(P<0.05或P<0.01)。结论:肥胖、高血压、高血脂等是2型糖尿病合并非酒精性脂肪肝患者的相关危险因素。

Objective： To research the risk factors of non-alcoholic fatty liver combined with diabetes type II and the relationship of metabolic syndrome. Method： Divide diabetes type II into non-alcoholic fatty liver combined with diabetes type II group （group A） and simplex diabetes type II group （group B）. Then compare and analyses the clinical information, such as body mass index （BMI）, systolic blood pressure （SBP）, diastolic blood pressure （DBP）, glycated hemoglobin HbA1C, total cholesterol （TC）, LDL cholesterol （LDL）, triglyceride （TG）, alanine aminotransferase （ALT）, Aspartate aminotransferase （AST） and γ-glutamyl transferase （GGT） and so on. Result： There are no significant difference between the two groups of gender, age and duration （P〉0.05）. There are no significant difference between T2DM patients group without fatty liver and T2DM patients group with fatty liver in FBG, 2hBG, HbA1C and LDL-C （P〉0.05）. The ISI and HDL-C of T2DM patients group with fatty liver is lower then T2DM patients group without fatty liver＇s. And TC, TG, FINS, 2hiNS and BMI increased （P〉0.05 or P〉0.01）. Conclusion： The risk factors of non-alcoholic fatty liver combined with type 2 diabetes patients are obesity, hypertension, high cholesterol, etc.