丙泊酚分步靶控输注对老年患者围插管期血流动力学的影响

Influence of multistep propofal TCI induction on haemodynamic fluctuation in the elderly

目的：与常规丙泊酚靶控方式比较,评估分步丙泊酚靶控对老年患者围插管期血流动力学的影响。方法：选择年龄66~75岁,体重47-65kg,ASAⅠ-Ⅱ级,拟在全麻下行择期胃肠道手术患者30例,根据丙泊酚的不同靶控方法分为分步靶控组（S组）和常规靶控组（C组）每组15例,分步靶控组采用丙泊酚分步靶控法进行诱导,常规组采用常规靶控方法诱导。观测指标：记录有创动脉血压,心率气管插管前后共13个时间点,时间间隔1min。并计算血压变异（BPV）。结果：两种靶控诱导方式动脉血压无明显组间差异（P〉0.05）。不同诱导时相变化的趋势不同（P〈0.05）,心率无明显组间组内差异（P〉0.05）血压变异不同（P〈0.05）。结论：与丙泊酚常规靶控输注相比,丙泊酚分步靶控输注控制血流动力学波动更平稳合理。

Objective：To evaluate the influence of multistep propofal TCI induction on haemodynamic fluctuation in the elderly by its comparison with common propofal TCI induction.Methods：We selected 30 ASAⅠ~Ⅱelder patients, aged 66～79 years old,weighting 47~65kg,who scheduled for elective gastrointestinal tract surgery,and divided them into two groups according to TCI method：common TCI group and multistep TCI group with 15 in each.Meanwhile we recorded the blood pressure and heart rate at 13 time points before and after tracheal intubation,with an interval time of one minute and calculated the BVP.Results：There were no significant differences in the blood pressure between the two groups（P〉0.05）.There were significant differences between different time phases（P〈0.05）.There were no significant differences in the heart rate between the two groups and different time phases.There were significant differences in BPV between the two groups（P〈0.05）.Conclusion：The multistep TCI is more reasonable and stable than common TCI in controlling haemodynamic fluctuation