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羟喜树碱治疗骨髓增生异常综合征疗效观察

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摘要 目的观察羟喜树碱对骨髓增生异常综合征RAEB和RAEB-T化疗的治疗效果。方法临床通过对42例骨髓增生异常综合征RAEB及RAEB—T患者随机分为2组。治疗组(n=21):给予羟基喜树碱+阿糖胞苷,对照组(n=21):给予柔红霉素+阿糖胞苷。对症支持治疗基本相同。结果羟基喜树碱+阿糖胞苷的疗效与柔红霉素+阿糖胞苷基本相同,但它的化疗毒性(骨髓抑制及消化道)明显减轻。结论羟基喜树碱作为一种抗肿瘤药物在骨髓增生异常综合征治疗中疗效确切,副作用相对较低,值得推广。
作者 王爱梅
出处 《医学信息》 2011年第5期1245-1246,共2页 Journal of Medical Information
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