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埃索美拉唑联合伊托比利治疗反流性食管炎的疗效分析 被引量:1

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摘要 目的探讨埃索美拄唑与伊托必利联合治疗反流性食管炎(RE)的疗效。方法选择82例经内镜确诊的反流性食管炎患者,随机分为2组。治疗组42倒,口服埃索美拉唑20mg,2次/d,同时服用伊托必利10mg,每目3次。对照组40例,口服埃索蔓拉唑20mg,2次/d,疗程均为8周,分别比较两组临床症状和内镜下改变的临床疗效。结果治疗8周时。两组烧心症状、反酸症状、胸骨后灼病症状积分均较治疗前下降(P〈0.05)。治疗组症状下降更为显著,与对照组相比,差异有统计学意义(P〈0.05)。治疗组内镜下食管炎愈合率、总有效率明显优于对照组,差异有统计学意义(P〈0.05)。结论埃索美拉唑联合伊托必利治疗RE疗效优于单用埃索美拉唑,是治疗RE的有效方法之一。
出处 《医学信息》 2011年第5期1281-1282,共2页 Journal of Medical Information
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