马来酸桂哌奇特治疗偏头痛性眩晕的疗效观察

The effect of cinepazide Injection in treating migrainous vertigo

目的 观察马来酸桂哌奇特注射液治疗偏头痛性眩晕（migrainous vertigo,MV）的疗效.方法 选择2006年3月～2009年3月在本院门诊就诊的偏头痛性眩晕患者90例,随机分为治疗组和对照组.治疗组45例,给予马来酸桂哌奇特注射液治疗.对照组45例,给予银杏达莫注射液治疗. 治疗前、治疗后对2组患者进行头痛程度、头痛频率、眩晕缓解率、远期疗效观察,并进行疗效比较.采用视觉模拟评分法（visual analogue scale,VAS）比较两组治疗前后头痛程度的变化.结果 治疗后两组头痛程度（χ2=10.152,P＜0.05）、头痛频率（χ2=11.322,P＜0.05）、眩晕缓解率（χ2=10.152,P＜0.05）、复发率（χ2 =6.15,P＜0.05）有显著性差异.结论 马来酸桂哌奇特注射液治疗偏头痛性眩晕安全有效,且疗效优于银杏达莫.

Objective To oberve the effect of cinepazide injection in treating migTainous vertigo. Methods 90 out - patients with migrainous vertigo from March 2006 to March 2009 were included in this study. The age, the length of headache, the headache history of family, the frequency of headache, the degree of headache and the degree of vertigo were recorded. They were randomly divided into the treatment group （n = 45 ） and the control group （n = 45 ）. The treatment group was treated with cinepazide injection. The control group was treated with Ginkgo biloba extract and dipyridamole injection. The changes of headache degree, headache frequency,the remission rate of vertigo and the relapse rate were compared after treatment. The curative effects of the two groups were compared with visual analogue scale （VAS）. Results Both the two group were statistical differences on the degree of headache（x^2 = 10. 152,P 〈0. 05） ,the frequency of headache （X^2 = 11. 322,P 〈0. 05） the remission rate of vertigu（X^2 = 10. 152 ,P 〈 0. 05 ）and the relapse rate（x^2 = 6. 15 ,P 〈 0. 05 ）. Conclusion Cinepazide injection can control the migrainous vertigo effectively, it has better efficiency than Ginkgo biloba extract and dipyridamole injection.