卡孕栓防治产后出血60例临床观察

The clinical observation of methyl carprost suppositories on the postpartal hemorrhage in 60 patients

目的 探讨卡孕栓防治产后出血的效果.方法 对60例同期正常足月妊娠阴道分娩的产妇,按交叉设计方法随机分为实验组和对照组.实验组28例,于胎儿娩出后,将卡孕栓2枚（1 mg）置直肠或舌下含化;对照组32例,于胎儿娩出后静推缩宫素20 IU,入液静滴缩宫素30～40 IU维持.结果 实验组和对照组相比第三产程时间及产后2 h、24 h出血量都存在显著性差异（P〈0.01）,实验组的第三产程比对照组的第三产程缩短2～4 min,产后2 h内出血量减少60～120 ml.结论 卡孕栓与催产素相比,也具有子宫收缩作用,减少产后出血,且给药方便,具有安全性,有待推广.

Objective To explore the effects of methyl carprost suppositories to prevent postpartal hemorrhage. Meth- ods 60 pregnancies of the normal full - term vaginal delivery were divided into experimental and control groups, according to crossover design randomly. The group of experimental included 28 cases, using the sublingual or rectal I nag methyl carprost suppositories after delivery; The group of control included 32 cases, injecting 20 IU Gongti oxytocin and maintaining 30 -40 IU by intravenous infusion after delivery. Results The third time of bearing with the goup of experimental reduce 2 - 4 mi- nutes compared with the goup of control, reduce the amount of postpartal haemorrhage about 60 - 120 ml within 2 h also. Con- clusion Methyl carprost suppositories has uterine contractions, and can reduce the amount of postpartal haemorl＇hage, and has a convenient administration, safe characteristics to be promoted.