反复呼吸道感染患者与晚发性佝偻病及锌缺乏的关系

Relation between recurrent respiratory infections, delayed rickets and zinc deficiency in children

目的 了解反复呼吸道感染患儿与晚发性佝偻病及锌缺乏的关系。方法 观察 1994年 9月至 1996年 11月间 6 0例 5岁以上反复呼吸道感染患儿及 5 6例健康儿童血清钙、磷、碱性磷酸酶、锌含量及左腕骨X线放大摄影片的骨龄发育。结果 观察组血清钙、磷、锌较对照组低 ,碱性磷酸酶明显高于对照组 ;观察组 37例合并晚发性佝偻病 ,31例合并锌缺乏症 ;明显高于对照组 (P <0 0 1) ,经应用VitD3、锌剂治疗后其血清钙、磷、碱性酶、锌及左腕骨X线异常于 3个月内恢复 ,呼吸道感染次数明显减少。结论 表明做好晚发性佝偻病及锌缺乏症的防治是防治反复呼吸道感染的关键。

Objective To study the relation between recurrent respiratory infection, delayed rickets and zinc deficiency in children. Methods\ To observe 60 infants aged above 5 years with recurrent respiratory infection, and 56 healthy infants for the contents of serum calcium, phospharus, alkaline phosphatase, and zinc as well as the development of bone age by magnifying left carpal bone with the X ray machine.Results\ The contents of serum calcium, phosphorus and zinc in the study group were lower than those in the control group, but the content of alkaline phosphatase was remarkably higher than that in the control group; in the study group 37 infants were complicated with delayed rickets, 31 with zinc deficiency; which was notably higher than that in the control group(P<0.01);after treament with Vit D 3 and zinc agent, their serum calcium, phosphorus, alkaline phosphatase and left carpol bone abnormalities returned to normal within three months, the frequency of respiratory tract infection decreased remarkably. Conclusion\ This shows that better prevention of delayed rickets and zinc deficiency is the crux of curing recurrent respiratory tract infection.