成人仰卧位肺功能1秒钟用力呼气容积与最大通气量的相关性研究

Study of Correlation between FEV1 and MVV in Adults in Supine Position

目的探讨成人仰卧位1秒钟用力呼气容积(FEV1)与最大通气量(MVV)的相关性。方法回顾性分析我院2000年12月—2010年1月因下肢骨折住院的2 790例成年患者的仰卧位肺功能资料。应用Pearson相关分析FEV1和MVV的相关性,一元线性回归分析建立MVV与FEV1线性回归模型,并进一步分析MVV估测值与实测值之间的差距。结果 MVV与FEV1呈正相关(r=0.781,P<0.01),MVV与FEV1直线回归方程为MVV=29.374×FEV1+4.92(t=4.468,P<0.01),根据此回归方程估测的MVV值与实测值之间呈正相关(r=0.781,P<0.01)。结论成人仰卧位FEV1可预测MVV,该回归方程可用于下肢骨折患者的手术风险和术后康复的评估。

Objective To investigate the correlation between forced expiratory volume in 1 second（FEV1） and maximal voluntary ventilation（MVV） in adults in supine position.Methods FEV1 and MVV of supine position were studied retrospectively in 2790 adult patients with lower leg fractures admitted from December 2000 to January 2010 in our hospital.The correlations between FEV1 and MVV were assessed using the Pearson correlation coefficient and regression analysis.Results Pearson linear correlation showed a positive correlation of MVV with FEV1（r=0.781,P0.01）.The unitary linear regression model produced the following equation：MVV=29.374×FEV1＋4.92（t=4.468,P0.01）;Positive correlation was identified between the expected value and measured value of MVV（r=0.781,P0.01）.Conclusion Our results suggest a correlation between FEV1 and MVV in adults in supine position.We consider the equation as a useful tool for the risk assessment of lower leg fracture surgery and prediction of postoperative rehabilitation.