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伊立替康联合5-氟尿嘧啶治疗晚期胃癌的临床分析 被引量:2

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摘要 目的:评价伊立替康联合5-氟尿嘧啶治疗晚期胃癌的临床疗效和毒副反应。方法:对32例晚期胃癌患者采用伊立替康联合5-氟尿嘧啶方案化疗治疗,连用4个周期。结果:全组32例均可评价疗效,其中完全缓解2例,部分缓解11例,稳定14例,进展5例,总有效率40.6%。中位缓解5个月,中位TTP4.5个月,中位生存7.2个月。毒副反应主要为骨髓抑制、迟发性腹泻、恶心呕吐等,未见因毒副反应而终止治疗者,无治疗相关性死亡。结论:伊立替康联合氟尿嘧啶、亚叶酸钙双周方案治疗晚期胃癌耐受性较好,疗效较满意,有临床应用价值。
出处 《中国社区医师(医学专业)》 2011年第7期51-51,共1页
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