小剂量黛力新联合思连康治疗肠易激综合征疗效观察

目的:小剂量氟哌噻吨美利曲辛联合双歧杆菌四联活菌治疗肠易激综合征的疗效观察。方法:将肠易激综合征患者80例,随机分成两组,联合治疗组(n=40)和对照组(n=40)。联合治疗组予氟哌噻吨美利曲辛1片,3次/日,早上服用,双歧杆菌四联活菌1.5g,3次/日。对照组予双歧杆菌四联活菌1.5g,3次/日。疗程4周,观察疗效。结果:联合治疗组总有效率92.5%,对照组总有效率62.5%,联合治疗组总有效率明显优于对照组(P<0.01)。两组患者均未发现不良反应。结论:小剂量氟哌噻吨美利曲辛联合双歧杆菌四联活菌能够有效治疗肠易激综合征。

Objective：To investigate effects of low dose Flupentixol/Melitracen combining Live Combined Bifldobacterium, Eactobacillus,Enterococcus and Bacillus Cereus Preparation in treating irritable bowel syndrome. Methods： 80 patients with irritable bowel syndrome were randomly divided into two groups ：the combined treatment group （n = 40） and the control group（ n =40）. The patients in combined treatment group took Flupentixol/Melitracen one time daily in early morning and Live Combined Bifidobacteriurn, Lactobaciltus, Enterococcus and Bacillus Cereus Preparation 1.5g three times daily orally, the control group took Live Combined Bifidobactefium, Laetobacillus, Enterococcus and Bacillus Cereus Preparation 1.5g three times daily orally,the courses of treatment were 4 weeks, to observe and compare the therapeutic effect between the two groups. Results：The total effective rate was 92.5% in combined treatment group, and 62. 5% in control group. The total effective in combined treatment group was significantly higher than that of control group （P 〈 0. 01）. All patients without adverse reactions. Conclusion： Low dose Flupentixol/Melitracen combining Live Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Preparation has good therapeutic effect on irritable bowel syndrome.