高龄因素对妊娠结局的影响

The Influences of Age on Pregnancy Outcome

目的分析高龄孕妇年龄对妊娠结局的影响。方法采用回顾性对照研究,分析2005年1月～2010年12月在我院住院分娩的716例高龄单活胎孕妇的临床资料,按年龄分为A组(年龄40～44岁)和B组(年龄35～39岁),比较两组高龄孕妇分娩方式、妊娠合并症和并发症以及新生儿结局的差异。结果高龄孕产妇发生率逐年递增;高龄孕妇两个年龄组妊娠合并及并发症发生率均明显增加,年龄组(40～44岁)孕妇发生妊娠期高血压疾病重症的发生率、剖宫产率显著高于年龄组(35～39岁),有统计学差异;两组新生儿畸形率及围产儿死亡率差异无显著性。40岁以上初产妇组与经产妇组比较,经产妇组妊娠合并症及并发症的发生率无统计学差异;两组剖宫产率比较无统计学差异,初产组以高龄产妇单一手术指征的剖宫产率高于经产组,有统计学差异。结论高龄孕妇随年龄增长,妊娠合并症与并发症的发生率随之增长,剖宫产率升高。

Objective To investigate the influences of age on pregnancy outcome in advanced pregnancy women. Methods 716 cas- es of advanced maternal age delivered in our hospital from January 2005 to December 2010 were analyzed by retrospective control review. To compare the difference of delivery methods, complications, neonatal outcome between group A （aged from 40 - 44） and group B （aged from 35 - 39）. Results The incidence of advanced age pregnancy increased year by year, the incidence of pregnancy complications in- creased obviously in both group A and group B, the incidence of pregnancy-induced hypertension and the rate of cesarean section were sig- nificantly higher in group A than group B （P 〈0.05）; the rate of abnormal newborn and perinatal mortality rate had no significant difference （P 〉0.05）; the incidence of pregnancy complications and rate of cesarean section had no significant difference （P 〉0.05） in multiparas aged from 40 - 44; the rate of cesarean section caused by advanced age in primipapas was significantly higher than pluripapas （P 〈0.05）. Conclusion The incidence of the pregnancy complications and the rate of cesarean section obviously increase with the development of age.